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First, we investigated effect of BPC 157 on vasomotor tone of blood vessel to study if it was in an endothelium- or nitric oxide-dependent manner
doi: 10.1111/wrr.12520
Management depends on B12 supplementation, either via high-dose oral routes or via parenteral administration
the FDA has stated it lacks sufficient information to know whether the substance would cause harm when administered to humans Evidence snapshot: The evidence base is almost entirely preclinical, decades of animal (largely rat) studies, mostly from one Croatian research group (Sikiric et al., University of Zagreb), with a single small human trial under the brand name "Bepecin" (around 2015) that did not lead to any FDA-approved use
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