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Sodium butyrate, a histone deacetylase inhibitor, reverses behavioral and mitochondrial alterations in animal models of depression induced by Early- or Late-life stress
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[78] using a combination of in vitro and in vivo assays, have demonstrated that Epimedin B increases melanin production and promotes both melanosome biosynthesis and transport through AKT-mediated GSK3/-catenin, p70 S6 kinase cascade, p38/MAPK, and ERK/MAPK signalling pathways
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