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Description

Semaglutide is a longacting investigational GLP1 receptor agonist (GLP1RA) studied for its effects on glycemic control and bodyweightrelated endpoints in controlled research settings

It followed up with Zepbound for weight loss, which was approved in 2023

This slow escalation helps improve tolerability, as the gastrointestinal side effects are often dose-related

Breaking down the data To illustrate how orforglipron fits within the landscape of current and emerging therapies, the following table highlights key endpoints from separate trials