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Rather than suppressing caloric intake, they may enhance substrate utilization, preserve lean mass, and improve metabolic resiliencefeatures particularly relevant to aging populations, where sarcopenia, osteoporosis, and insulin resistance frequently coexist

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Whether that tolerability advantage holds at longer durations is still an open question this interim cuts at Week 20 in a 60-week study

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These drugs mimic the action of a naturally occurring hormone called glucagon like peptide 1

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