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Timing Considerations Because GLP-1 medications can influence metabolism and potentially early pregnancy, many reproductive endocrinologists recommend pausing these medications when trying to conceive or during IVF cycles
However, these same protective mechanisms create a major pharmacological bottleneck, particularly for biologics such as antibodies, enzymes, and nucleic acid-based therapeutics exceeding 400-500 Da
Naegelen I, Beaume N, Plancon S, Schenten V, Tschirhart EJ, Brechard S
doi: 10.1126/scitranslmed.aar7047
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