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Prevention: administer for 2 consecutive days
The BBB employs various transport systems, such as carrier-mediated transport (CMT), receptor-mediated transport (RMT), active efflux transport, vesicular trafficking by transcytosis, and ion transport, to facilitate the entry of essential substances into the brain parenchyma and the efflux of metabolic waste and endogenous neurotoxins [19, 23]
For example, Vitamin C and Vitamin E help "recharge" glutathione after it has neutralized a free radical
There might be other pathways/genes account for the differences
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