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Ussher JR, Campbell JE, Mulvihill EE, Baggio LL, Bates HE, McLean BA, Gopal K, Capozzi M, Yusta B, Cao X, et al

Press the injection button firmly and hold it down for the duration specified in your device instructions: For Ozempic/Victoza/Saxenda: keep the button pressed until the dose counter returns to '0' and count slowly to 6 For Trulicity: press the injection button, listen for the first click, then wait for the second click/grey indicator For other devices: follow the specific timing in your instructions After the required time, release the injection button first , then withdraw the needle straight out from the skin

It is not clear whether this is due to the drugs themselves or the weight loss that they cause

Suboptimal thyroid function, insulin resistance, sex hormone decline, and nutritional deficiencies can all produce an overlapping symptom picture