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Moreover, the S-0.9 mg 1-10 hydrogel formulation resulted in a mean reduction in average BG of 29 4%, similar to the S-0.9 mg 2-10 hydrogel formulation, and was also significantly more efficacious than the daily 20 g semaglutide treatment ( P = 0.0043, Figure 5A)

Fiber and injectable GLP-1 medications For injectable semaglutide , tirzepatide , and retatrutide , there is no direct absorption interaction with fiber supplements since the medication enters through subcutaneous injection, bypassing the digestive system entirely