Diabetes 45:10241029 Heitzer T, Finckh B, Albers S, Krohn K, Kohlschutter A, Meinertz T (2001) Beneficial effects of alpha-lipoic acid and ascorbic acid on endothelium-dependent, nitric oxide-mediated vasodilation in diabetic patients: relation to parameters of oxidative stress
Cihankaya H, Bader V, Winklhofer KF, Vorgerd M, Matschke J, Stahlke S, Theiss C, Matschke V (2024) Elevated NLRP3 inflammasome activation is associated with motor neuron degeneration in ALS
Its effect likely arises from the modulation of the extracellular matrix and the reduction of oxidative and inflammatory stress at the tissue level [2]
Although the physiological role of ferroptosis remains unclear, it can be triggered by pharmacological disruption of cellular lipid peroxidation repair or by oxidative stress associated with degeneration