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The effect of exercise training on osteocalcin, adipocytokines, and insulin resistance: a systematic review and meta-analysis of randomized controlled trials
10.1172/JCI30085 43
The second step in BH 4 synthesis, catalyzed by 6-pyruvoyltetrahydropterin synthase, involves the Zn 2+ and Mg 2+ -dependent rearrangement of 7,8-dihydroneopterin triphosphate, with concomitant loss of the triphosphate, to 6-pyruvoyltetrahydropterin
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