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IFN-, in turn, induces keratinocytes to highly express CXCL9/CXCL10 through the JAK-STAT pathway, recruiting more autoreactive CD8 T cells and forming a vicious cycle of oxidative stress-immune attack (Figure 1)

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The post exercise oxidative signal is part of how muscles get stronger, and saturating it with antioxidants right at that window can blunt training adaptations

When exposed to high ambient temperatures, the body diverts blood from the core to the skin surface to dissipate heat through vasodilation