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Drawing semaglutide to 25 units on a U-40 syringe would deliver 0.625 mg, not 0.25 mg
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The affected genes included critical "node molecules" (YWHAB, MAP3K5, LMNA, APP, GNAQ, F3, NFATC2, and TGM2) involved in regulating multiple biochemical pathways
Conversely, it may be that cell types that express only one receptor (such as adipose tissue, which only makes GIPR) or certain neuronal populations are less affected by higher doses of tirzepatide
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