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Topical application of SKQ1 eye drops 23 times per day for 46 weeks has been shown to increase tear film stability, reduce corneal fluorescein staining, and alleviate DE symptoms such as dryness, burning, foreign body sensation, and blurred vision [17, 174]
Once weight loss is achieved, the CO2 Fractional Laser treatment is administered to address skin laxity and aesthetic concerns
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Osteogenesis however is activated and shows increased expression of ALP , COL1 , OCN and RUNX2
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