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Usually, visible improvement is noticed within 2 weeks and the final effect of the application develops in 4-8 weeks

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Ethical Approval The entire experiment on animals was carried out in accordance with the Ethics Committee for Animal Experiments of the Institute of Animal Physiology and the State Veterinary and Food Administration of the Slovak Republic (Ro 3236/19-221/3)

In modern kamb sessions, the dried secretion is usually mixed with water and applied to small superficial burns on the skin, commonly called gates or gateways. A common application may involve three small points on the upper arm, though some practitioners use other areas such as the wrist, ankle, leg, or back, depending on the individual, tradition, and intention