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However, complex diseases such as obesity, type 2 diabetes, and neurodegenerative disorders are increasingly understood as network-level dysregulations rather than single-pathway failures

SDF-1, also referred to as CXCL12, functions as a chemotactic cytokine and proangiogenic chemokine, which enhances hematopoietic and endothelial progenitor cell recruitment to sites of cell injury

Cell culture applications utilize concentrations of 10-50 M for effective senescent cell elimination, with administration durations typically 24-72 hours depending on experimental objectives and cellular models