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Importantly, response seems more closely tied to biology (inflammation, obesity) than to the MTHFR genotype alone
This is useful after surgery, or in cases of skin or tissue damage
Urology 71 , 10011006 (2008)
Another study in colonic-sensitized rat models demonstrated that exendin-4 treatment dose-dependently reduced visceral hypersensitivity by upregulating serotonin transporter (SERT) expression and downregulating tryptophan hydroxylase-1 (TPH-1) expression [57]
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