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In particular, the 55 most highly expressed genes in the invasive MC58 strain included genes encoding proteins involved in amino acid transport and metabolism ( argH , aroA , aroB , ilvC , and gdhA ), genes for ATP synthase subunits ( atpA , atpD , atpG ), genes involved in sialic acid capsule biosynthesis ( siaB , siaC ), and an operon encoding Na + -translocating NADH-quinone reductase subunits ( nqrB , nqrC , nqrD )
Protocol as for acetaminophen toxicity: 140 mg/kg IV initially: slow bolus not constant rate infusion (ammonia toxicity) then 70 mg/kg IV or PO x 3-6 (or more) treatments given at 8 to 12 hour intervals
Others using less rigorous methods default to 14 to 28 days
Common Side Effects Injection site reactions account for the vast majority of reported side effects
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