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Ensuring adequate hydration is therefore an important consideration with GLP-1 RA treatment, as is recommended by the label, particularly for people with renal impairment, as dehydration is known to be associated with renal dysfunction [98]
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This early response may reflect the body's immediate utilisation of available B12 for urgent metabolic processes
A fundamental cause for this challenge is the heterogeneity in the IBS-D population and therefore, the inability of finding the specific mechanism that is causing the symptoms that need to be targeted in individual patients
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