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However, in one meta-analysis, adding 1.1g/kg of body weight, or .5g/lb of body weight, to water drunk before exercise increased fluid retention by 50% compared to water alone

[3] A common repletion strategy in profoundly deficient adults involves 100,000 IU intramuscularly every four weeks for two or three doses or a one-off 300,000 IU injection followed by oral maintenance

While their mechanisms may differ, their combination has been proposed to provide complementary or synergistic actions

la Torre R, De SD, Sola MP, Duchon A, Martnez M, de Lagran M, Farr MF et al (2014) Epigallocatechin-3-Gallate, a DYRK1A Inhibitor, Rescues Cognitive Deficits in Down Syndrome Mouse Models and in Humans