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DAMPs activate inflammation by activating toll-like receptors (TLR), a family of pattern recognition receptors (TLR1-10) expressed on lymphocytes, macrophages, and dendritic cells
While both options support significant weight reduction, tirzepatide has shown slightly higher results in trials, making it a strong choice if weight loss is your primary goal
Additionally, most of the human evidence is derived from small randomized controlled trials and a number of observational studies with moderate risk of bias, which limits the certainty and generalizability of conclusions
2005 May;93(4):1047-56
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