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For human xenograft studies, 2 10 6 HCT116 cells were transplanted 1:1 in Growth Factor Reduced Matrigel (Corning, CLS356231) into athymic nude mice (purchased from Inotiv), and the volume was calculated using the formula ( a b 2 )

But in rare cases, dumping syndrome can develop without a history of surgery or other obvious causes

Additionally, previous research has shown that elevated blood sugar levels activate p53 [104, 105], which enhances cellular sensitivity to ferroptosis by suppressing SLC7A11 expression and reducing cystine uptake [106]