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To investigate how IGF-1 contributes to PD-L1 regulation, we tested effects of inhibiting signaling pathways of IGF-1R and its downstream effectors MEK-ERK and AKT in DU145 prostate cancer cells
C ch hot ng ca I-glutathione L-glutathione trng da hot ng theo 2 c ch ring bit, gm c ch enzyme Tyrosinase v tng cng tng hp pheomelanin
doi: 10.1074/jbc.274.20.13908 41 IslingerMLiKWSeitzJVlklALersGH
However, the addition of trisomy 21 in the first case, and raised adenosine in the second, brings the profiles much closer to those observed in patients with Down syndrome and autism, respectively
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