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Seek urgent medical attention if you develop severe or persistent abdominal pain (which could indicate pancreatitis), signs of gallbladder disease, or significant vomiting that could lead to dehydration

Maintenance Therapy and Tapering Once your symptoms are under control for several months, your provider may recommend a maintenance dose - usually 50100 mg/day - that can be continued long-term as long as potassium and kidney function remain normal and effective contraception is maintained

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1,2 No increase in serious heart events (heart attack, stroke) has been reported, but a dedicated cardiovascular outcomes trial is still pending