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The nutrients that trigger GLP-1 secretion are macronutrients simple sugars (monosaccharides), peptides and amino acids (from proteins) and short chain fatty acids (from fats and also produced by good gut bacteria)
doi: 10.1093/lifemeta/loae018 19 WanXXuCLinYLuCLiDSangJet al
Loss of appetite: Like other stimulants, Vyvanse suppresses hunger, which results in weight loss over time
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