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5.4 Acts by modulating gene expression in the intestinal microbiota In addition to regulating the gene expression of BSH of probiotic bacteria (described previously, see Chapter 4.3), metformin also modulates the protein-coding genes of another microbiota

A human glucagon-like peptide-1 receptor polymorphism results in reduced agonist responsiveness

Human studies found that adults taking 3 g of glycine before bed fell asleep more easily, slept more deeply, and showed improved next-day cognition, suggesting benefits for mental clarity and stress resilience

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