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this occurs because there is not enough vitamin B12 in the diet, or poor absorption Pernicious anemiaa type of megaloblastic anemia caused by a lack of intrinsic factor, so that vitamin B12 is not absorbed Fatigue, weakness Nerve damage with numbness, tingling in the hands and legs Memory loss, confusion Dementia Depression Seizures Up to 15% of the general population has a B12 deficiency

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99 Other studies involving 3T3-L1 cells showed that genistein inhibits adipocyte formation through activation of AMPK, induces apoptosis in mature adipocytes, 100 inhibits the phosphorylation of P38 MAPK, and prevents C/EBP expression

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