The third is biosynthetic and signaling use: anaplerosis, amino acid signaling, protein acetylation, lactylation, succinylation, and kinase pathways such as AMPK, mTOR, PKA, and YAP
A typical strategy is a short trial, evaluate response, then repeat cycles as clinically indicated while addressing lifestyle and underlying drivers
Materials and methods Experimental animals The animal experiments were performed on the basis of ethical regulations for animal testing, and the animal protocol employed in this study was approved by the Animal Experimentation Committee of Jinan University (IACUC-20191212-02)
Liao H-J, Chen H-T, Chang C-H