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MOTS-c is a mitochondrial-derived peptide that regulates metabolic pathways and helps with the proper utilization of fatty acids for energy
The medications do most of the work
The findings are compatible with the clinical data showing that fibroblasts derived from a patient with homozygous A71P mutant in CHCHD2 show reduced cIV activity in addition to cI deficiency (Lee et al., 2018)
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