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Oral cimetropium bromide, a new antimuscarinic drug, for longterm treatment of irritable bowel syndrome
The mechanism involves inhibition of nitric oxide synthase (NOS) activity: glutathione binds nitric oxide (NO), a critical neurotransmitter in gut motility, effectively sequestering it before it can signal smooth muscle relaxation and coordinated peristaltic waves
First-trimester exposure to metformin and risk of birth defects: a systematic review and meta-analysis
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