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The effect of a levonorgestrel-releasing intrauterine device in the treatment of myoma-related menorrhagia

Although metformin increased GLP-1R level, exendin (939) or GLP-1R siRNA did not attenuate the protective effects of metformin in PA-impaired HUVECs, suggesting that metformin per se could not exert protective effects via GLP-1R, instead, metformin upregulated GLP-1R to enhance the protective effects of liraglutide on endothelial function

Nausea, vomiting, diarrhea, and constipation are common, especially during dose increases, and GI (gastrointestinal) symptoms are common reasons people stop treatment

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