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GLP-1 medications are currently considered long-term treatments

These complementary effects on fat and muscle catabolism suggest that GLP-1 RAs may help preserve skeletal muscle integrity while concurrently improving metabolic efficiency in the context of obesity-related muscle dysfunction

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Usual Adult Trulicity Dose for Cardiovascular Risk Reduction: Initial dose: Trulicity 0.75 mg subcutaneously once a week The dose may be increased to 1.5 from 0.75, then in 1.5 mg increments for additional glycemic control