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Sitagliptin inhibits DPP4, the enzyme that breaks down incretin hormones
Similarly, gut microbiota-derived trimethylamine-N-oxide (TMAO) has been closely linked to metabolic disturbances in PCOS
Jardiance also interacts with lithium, which can result in decreased lithium levels and can make lithium less effective
it's a reflection of the funding economics of unpatentable compounds
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