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It also states that compounded semaglutide should never be initiated, adjusted, or discontinued without medical supervision
If you are taking oral contraceptive pills and starting tirzepatide or increasing your dose, the FDA recommends implementing additional contraceptive protection
2020 [cited 2022 Jan 1];43:53440
Treatment stage What may be common What deserves attention Week 1 Nausea, fullness, reduced appetite, bloating, indigestion, diarrhea, constipation, fatigue Repeated vomiting, severe pain, inability to stay hydrated Weeks 2 to 4 Early symptoms may settle, persist, or fluctuate Symptoms interfering with eating, drinking, or daily function Weeks 5 to 8 Symptoms may reappear after clinician-directed dose escalation A significant return or worsening of gastrointestinal symptoms Months 2 to 3 Some patients tolerate treatment more comfortably
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