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The ulcerogenic effects of PGN were confirmed in Guinea pigs, monkeys, rats, and mice (Benitz et al
United States Patent Application US2005/0239164 (A1) Qian W, Xie H, Wu Q (2016) Method for preparing yeast fusants and screening glutathione high-yield strains
While its antioxidant activity may protect normal cells or basal tissues, its pro-oxidant activity at supra-physiological doses or in metal-rich microenvironments becomes a mechanism for curcumin to selectively kill cancer cells
PMC 6522248
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