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This may increase the risk of sarcopenic obesity, particularly in older individuals
10,11,15 Aging skin displays fragmentation of collagen and elastin fibers by the action of matrix metalloproteinase (MMPs), and increased mitochondrial oxidative stress results in deletions of mitochondrial DNA via the c-Jun/AP-1 pathway in dermal fibroblasts (Figure 1)
The in vitro data demonstrated that AOD9604 increases 3-AR expression in fat cells, contributing to enhanced lipolytic sensitivity
Though effective, it requires dedication of clinic visits every 12 to 16 days
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