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Thus research is now being directed at alternative strategies for increasing endogenous GLP-1 secretion, including stimulating G-protein coupled receptors expressed in L-cells such as TGR5 [26,27] and GPR119 [28]
Metabolism : Approximately 79% of sitagliptin is excreted unchanged in the urine with metabolism being a minor pathway of elimination
Drugs 26 , 231243 (2021)
However, every individual's circumstances and health needs are unique, and abruptly stopping these medications can carry potential risks
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