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When present, side effects are typically mild and may include vivid dreams or altered sleep architecture as the brain undergoes increased neuroplastic activity, mild headaches during initial therapy (often resolving within days), temporary changes in appetite, or subtle mood variations during the adaptation period

Together, these signaling systems provide a framework for investigating how angiogenic signaling, cytoskeletal organization, and fibroblast-mediated extracellular matrix processes interact in laboratory models of tendon, ligament, and musculoskeletal tissue biology

Early human trials have explored its efficacy in treating symptoms associated with gastrointestinal ulcers, osteoarthritis, and post-surgical recovery

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