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Because arginine competitively inhibits lysine transport into the CNS, it reduces the accumulation of P6C and -AASA [32]
In summary, FOXO4-DRI exerts its anti-aging effects by inhibiting the binding of FOXO4 to P53, promoting P53 phosphorylation, and facilitating the translocation of p-P53 from the nucleus to the cytoplasm for its functional role
doi:10.1126/science.169.3951.1208 Hawkins RA
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