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As a corollary, in response to oxidant stress, G6PD-deficient hepatocytes exhibit transcriptomic network perturbations in redox pathways and immune response pathways (98)

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Functional changes Phagocytosis Since monocytes and macrophages can enter the CNS in PD [28, 104], both cell types could be involved in the recognition of protein components and cellular debris [105, 106] and in the activation of phagocytotic mechanisms