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In addition to these widely used AOMs, Exenatide, one of the earliest GLP-1 RAs approved by the FDA and EMA for T2DM management, is not indicated for weight management but remains clinically relevant, particularly in older adults with comorbid obesity and T2DM, given its long-term clinical experience and established tolerability profile [26,27,28]

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Initially, 5 mg/mL suspension of DNZ-NLPs was added gradually to an equal volume of FITC (5 g/mL) and was then placed on the stirrer for 12 h at room temperature

The role of synovitis in pathophysiology and clinical symptoms of osteoarthritis