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Food and Drug Administration) Dosage and infusion rate : high doses or rapid infusion increase risk of systemic reactions (allergy, shock, organ stress)
Zimmermann MB
doi:10.1016/j.ensci.2021.100340 51
Should this pharmacological profile be confirmed in late-stage clinical studies, optimized FGF21 analogs have the potential to not only resolve liver pathology, but also to reduce risk of cardiovascular morbidity and mortality, and incidence of organ damage associated with inadequate glycemic control
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