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Researchers have proposed several non-exclusive frameworks, including blood-brain-barrier transport of an endogenous peptide, interaction with the stress axis, circadian and pineal signalling via the alpha-1-adrenergic receptor (PMID 3029331), and neuroprotective activity

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Clinician-guided GLP-1 care using semaglutide , with labs, gradual dose titration, and follow-ups

As reproduction and eating are both drives that are wired into the human system by evolution, Sultan said it makes complete biological sense that both of these needs are tied to the brains reward pathways