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J Cell Physiol 235(4):31573168 Assirelli E, Pulsatelli L, Dolzani P, Platano D, Olivotto E, Filardo G, Trisolino G, Facchini A, Borz RM, Meliconi R (2014) Human osteoarthritic cartilage shows reduced in vivo expression of IL-4, a chondroprotective cytokine that differentially modulates IL-1-stimulated production of chemokines and matrix-degrading enzymes in vitro
Cuando el cerebro envejece pierde mucha cantidad de neuritas provocando la disminucin y la reduccin de la eficacia de la mayora de los procesos cognitivos
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