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One challenge to elucidating a mechanistic role for GLP-1Rs stems from their complex expression across multiple brain regions (1012), including the lateral septal nucleus (LSc), substantia nigra, ventral tegmental area (VTA), amygdala, nucleus accumbens (ACB), hippocampus, several regions of the hypothalamus (paraventricular nucleus of the hypothalamus [PVH], arcuate nucleus [ARH]), and hindbrain
Understanding how maintenance works is key to protecting the progress youve already made, and avoiding the frustration of weight regain
| Placebo | 2.5 | 25 | 10 | 3 | 1 | 2
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