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GCL belongs to the class of proteins that are sensitive to oxidative stress, and its expression is mainly under the regulation of the Nuclear factor (erythroid-derived 2)-like 2 (NFE2L2), a transcription factor that regulates a wide array of antioxidant responsive element-driven genes in various cell types ( the novo GSH biosynthesis is glutathione synthase (GS)
19 , 19841992 (2005) Yao, M., Ma, L., Humphreys, W.G., Zhu, M.: Rapid screening and characterization of drug metabolites using a multiple ion monitoring-dependent MS/MS acquisition method on a hybrid triple quadrupole-linear ion trap mass spectrometer
It also enhances the activity of detoxification enzymes, such as glutathione S-transferases (GSTs), which conjugate toxins to Glutathione, facilitating their elimination (Lu, 2013)
Additionally, this treatment helps in minimizing dark spots which normally appear as a result of hormonal changes or too much sunlight
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