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This observation led to a study where GLP-1 was given to obese patients with T2DM and showed improved glycemic control with no side effects, establishing a proof-of-concept for GLP-1 agonists, which over time led to their use in the treatment of T2DM patients [21]

AR phase separation Despite these important new insights, because of the notoriously highly disordered structure of the AR NTD, the latter study used NTD-truncated AR to derive structural information, which may have limited the scope and the therapeutic potential of this information

Contact a licensed provider if side effects continue, progress stalls, symptoms feel concerning, or you have questions about dosing, continuation, or treatment safety