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They can help lighten dark spots and boost collagen when used consistently, though vitamin C is unstable and must be protected from light and air to remain effective
Preliminary evidence suggests NAD-boosting compounds (nicotinamide riboside, NMN, niacin) may improve mitochondrial function and insulin sensitivity in rodent and some human studies, but effect sizes remain modest
Butyrate has also been found to be a potent inhibitor of HDACs (83)
These effects are particularly relevant given the increased risks of cardiovascular and kidney diseases in patients with diabetes
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