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The peptide modulates the nitric oxide system, which is directly relevant to gastroparesis pathophysiology

For instance, the immediate surge of free Fe during reperfusion drives lipid peroxidation mediated by ACSL4/Alox15, and the peroxidation of mitochondrial cardiolipin leads to the opening of the mitochondrial permeability transition pore (mPTP), resulting in ferroptosis of cardiomyocytes

Ahsan H, Ali A, Ali R

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