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The peptide also increased expression of beta-3 adrenergic receptor RNA in fat cells of obese mice to levels comparable with lean mice, suggesting it helps normalize the fat-burning machinery that obesity suppresses
For in vitro studies, Caco-2 cell monolayers or other gut epithelial cell models provide a controlled system for examining barrier function
The Iba1-Cre transgenic mice are available from Yoshihiro Yoshihara under a material transfer agreement
11 12 This raises concerns about potential long-term effects on metabolic health, strength, and physical function
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