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According to the STEP 1 trial [1] protocol published in the New England Journal of Medicine, semaglutide dose escalation follows a specific 16-week ramp-up to minimize gastrointestinal side effects
Across these studies, the notion of food aversion and nausea through GLP-1 signaling has been implied, but there lacks sufficient evidence to support this claim [56]
A required Eden Membership ($99/month, disclosed in Eden's own footnote) sits on top, so the true all-in cost is $198/month for semaglutide and $298/month for tirzepatide
In the first few weeks of treatment, some individuals may experience mild gastrointestinal side effects such as nausea, bloating, or occasional diarrhea
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